Many species, however, use mechanisms that appear to be precursors of these aspects of vertebrate immunity. b) fever. The immune system can be divided into two overlapping mechanisms to destroy pathogens: the innate immune response, which is relatively rapid but nonspecific and thus not always effective, and the adaptive immune response, which is slower in its development during an initial infection with a pathogen, but is highly specific and effective at attacking a wide variety of pathogens (Figure 21.2.1). These include the in ammatory response, phagocytosis, natural killer cells, and the complement system. Functional system rather than organ system. This is the first line of defense against any microbial attacks on the baby. Specific Resistance (Acquired Immunity) Physical and Chemical Barriers (Innate Immunity) Physical and chemical barriers form the first line of defense when the body is invaded. Innate defenses do have specific pathways for certain substances. Together these defenses make up our immune system that can divide into the innate and adaptive immune system. Study Chapter 21: The Immune System: Innate and Adaptive Body Defenses flashcards. the Innate immune system are our non-specific first line of defense and include our macrophages, mast cells and complement proteins. Inside the castle, soldiers were ready to fight off any invaders that managed to get through the outer defenses. Both parts of the immune system work on different levels: Firstly, there are special defense cells in the different tissues that are directly involved in eliminating pathogens (germs). The immune system’s three lines of defense include physical and chemical barriers, non-specific innate responses, and specific adaptive responses. Second, the adaptive immune system is antigen specific and reacts only with the organism that induced the response. The innate sytem is the first line of defense. In fact, it has three lines of defense. There are two types of specific defense. Our body defenses help ward of damage and disease. The system can also remember pathogens and produce a powerful response the next time a pathogen enters the body. White blood cells in the blood and lymph recognize pathogens as foreign to the body. When pathogens enter the body, the innate immune system responds with a variety of internal defenses. These cells belong to the so-called cellular defense. These can be generally classified into mechanical defenses, anti-infective chemical defenses, cellular defenses, and chemokine or cytokine defenses. If innate immunity can't contain an infection, the adaptive immune system kicks in: T cells, B cells, and antibodies that bring specificity and memory. Play games, take quizzes, print and more with Easy Notecards. Innate Immune System Defenses Include A. Innate immune response. This response to viral infection consists of an innate, or nonspecific component, and an adaptive, or specific defense. The identification of the Toll pathway as a critical component of the host defense against fungal and Gram-positive bacterial infections in insects in 19964 provided the impetus for the subsequent identification o… Innate immune recognition relies on a limited number of germline-encoded receptors. If pathogens defeat these defenses and enter the body, the innate immune system responds with a arietvy of internal defenses. Animal immune systems include both innate and adaptive immune responses. In response to viral infection, many organisms mount a remarkable defense known as the immune response. The innate response is considered the first line of immune defense because it is active even before infection begins. The innate immune system provides this kind of nonspecific protection through a number of defense mechanisms, which include physical barriers such as the skin, chemical barriers such as antimicrobial proteins that harm or destroy invaders, and cells that attack foreign cells and body cells harbouring infectious agents. These mechanisms include physical barriers such as skin, chemicals in the blood, and immune system cells that attack foreign cells in the body. Innate immune cells also are important for activating adaptive immunity. Innate immunity is a part of the immune system which exists from the birth of an individual. An important role of the innate immune system in the first-line defense against pathogens and the underlying molecular and cellular mechanism(s) has recently been unveiled. Innate responses release proteins that alert cells of adaptive system to foreign molecules. Innate defenses include mechanical clearance, cellular responses provided by host phagocytes and molecular protection in the form of antimicrobial peptides. INNATE IMMUNE SYSTEM. The majority of infections by pathogens occurs in mucous membranes of our body. These recruited defense cells include: phagocytic cells: leukocytes such as neutrophils, eosinophils, and monocytes; tissue phagocytic cells in the tissue such as macrophages (def) ; cells that release inflammatory mediators: inflammatory cells in the tissue such as macrophages and mast cells (def) ; leukocytes such as basophils and eosinophils; and These receptors evolved to recognize conserved products of microbial metabolism produced by microbial pathogens, but not by the host. Also explore over 11 similar quizzes in this category. White blood cells in the blood and … There are three main lines of defense mechanisms: Pathogens and other non-self molecules are antigens – foreign molecules recognized by the immune system, stimulating an immune response. These cellular defenses identify … d) … It is also called natural immunity as it is a basic method of defense. The mechanisms include barriers such as the skin, chemicals in the … The function of the immune system is to protect the body from invasion and damage by different antigens, which can be microorganisms (bacteria, viruses, or fungi), toxins, and malignant cells. The innate immune system is an older evolutionary defense strategy, relatively speaking, and is the dominant immune system response found in plants, fungi, insects, and primitive multicellular organisms. Nonspecific Resistance (Innate Immunity) 3. The white blood cells are a key component. Cellular defenses of the innate immune response are non-specific. 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